Antiviral Agents, Vaccines and Immunotherapies by Stephen K. Tyring

By Stephen K. Tyring

In contrast to the other resource at the topic, Antiviral brokers, Vaccines, and Immunotherapies analyzes the advantages and obstacles of each on hand drug, vaccine, and immunotherapy used in the prevention and keep watch over of viral illnesses. This reference offers in-depth experiences of greater than 50 medications and antiviral brokers for HIV, human herpesviruses, human papillomaviruses (HPV), influenza, breathing syncytial virus, hepatitis B, and analyzes their mechanisms of motion, dosage, negative effects, and drug resistance. The ebook additionally offers an summary of using immunoglobulins and monoclonal antibodies for antiviral use and provides huge references, tables, and figures in the course of the textual content.

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Frequent genital herpes simplex virus 2 shedding in Introduction 23 immunocompetent women: effect of acyclovir treatment. J Clin Invest 99: 1092–1097. 8. , A. Wald, R. L. K. Tyring, T. Warren, et al. 2004. Once-daily valacyclovir to reduce the risk of transmission of genital herpes. N Engl J Med 350: 11–20. 9. P. 2002. Human papillomaviruses. K. ) Marcel Dekker, pp. 247–294. 10. J. Hance. 2004. HIV drug resistance. N Engl J Med 350: 1023–1035. 11. R. 2003. ” N Engl J Med 349: 2351–2352. 12. , V.

K. ) Marcel Dekker, pp. 247–294. 10. J. Hance. 2004. HIV drug resistance. N Engl J Med 350: 1023–1035. 11. R. 2003. ” N Engl J Med 349: 2351–2352. 12. , V. W. M. W. Snyder, and C. Pettinelli. 2003. ” N Engl J Med 349: 2293–2303. 13. M. K. Robbins, V. W. Snyder, and R. D’Aquila. 2003. ” N Engl J Med 349: 2304–2315. 14. De Clercq, E. 2002. New anti-HIV agents and targets. Med Res Reviews 22: 531–565. 15. Anonymous. 2003. ” MMWR 52: 1155–1157. 16. Enserink, M. 2003. ” Science 302: 1141–1142. Chapter 2 Antiretroviral Drugs to Treat Human Immunodeficiency Virus Infections INTRODUCTION In less than two decades, human immunodeficiency virus (HIV) has dramatically progressed from a little-known or understood infection to the cause of a major global epidemic.

Fever and malaise. Fever and malaise are rare. Ulcers. Oral and esophageal ulcers are rarely seen with ddI (65). One report notes Ofuji papuloerythroderma associated with ddI (66). Special Considerations Antacid and antibiotic coadministration. Didanosine is an acid-labile compound which is formulated with an antacid buffer. It should be taken on an empty stomach, at least 30 minutes prior to or 2 hours after a meal, in order to avoid an unfavorable acidic environment. , ciprofloxacin) and certain antifungals, such as ketoconazole and 44 Antiviral Agents itraconazole, require an acidic environment for absorption, and will be affected if administered with the antacid buffer found in didanosine.

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