Case Files: Biochemistry, 2nd Edition by Eugene C. Toy, William E. Seifert Jr., Henry W. Strobel,

By Eugene C. Toy, William E. Seifert Jr., Henry W. Strobel, Konrad P. Harms

Fifty scientific circumstances assist you excel in biochemistry classes and the USMLE Step 1

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Extra resources for Case Files: Biochemistry, 2nd Edition

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DISCUSSION DNA is the biological blueprint material, which authentically carries all the necessary cellular information and passes it from generation to generation. Thus, it is essential for the cells to preserve the integrity of the DNA and keep it as error free as possible. One is amazed with the versatile DNA molecule, which dictates both the unique and the similar features of the offspring from its parents. What are the processes that take place in a cell to duplicate and interpret this genetic code into functional signals?

In cases of chronic alcoholism, folate deficiency may result from poor nutrition or from poor absorption of folate secondary to a conjugase deficiency. Once folate deficiency occurs, abnormal megaloblastic replication of epithelial mucosa can occur, which further impairs folate uptake. After absorption, folate is reduced to THF by dihydrofolate reductase. The majority of circulating folate is in the form of N5-methyl THF. Cells use specific transporters for THF uptake, and cellular machinery polyglutamates the folate to aid in cellular retention.

His skin is warm to the touch, but no rashes are appreciated. The patient has mild cervical lymph node enlargement but otherwise has a normal examination. ◆ What is the most likely diagnosis? ◆ What is the biochemical mechanism of action of ribavirin? ◆ What is the genetic make up of this infectious organism? 18 CASE FILES: BIOCHEMISTRY ANSWERS TO CASE 2: RIBAVIRIN AND INFLUENZA Summary: A college student complains of the sudden onset of fever, chills, malaise, nonproductive cough, and numerous sick contacts in the fall season.

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