By Sudha R. Kini MD
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Additional info for Color Atlas of Differential Diagnosis in Exfoliative and Aspiration Cytopathology
Help to develop a consistent and uniform patient management strategy based on a “Pap” smear diagnosis; and 3. Provide recommendations. The Bethesda System (TBS) of reporting a cervical– vaginal cytologic diagnosis has three parts: 1. Specimen adequacy. 2. General categorization. 3. Recommendations (optional). Following the initial TBS, there had been two subsequent modifications in 1991 and 2001. For the detailed format of the reporting system, see Appendix. The statement on adequacy was long awaited.
H: Triphasic. Same case as above showing a glandular component. I: Triphasic. Same case showing a primitive cell component. I stromal, and blastemal) is triphasic. Synovial sarcoma is usually biphasic with epithelial and fibroblast-like spindle cells (Figs. 4F to I). Rarely will the tumor show only one pattern, which is referred to as monophasic. , monophasic synovial sarcoma). , adenosquamous). Cell Shapes Various epithelial, mesenchymal, and hematopoietic cells present different shapes and sizes, which are consistent in their euplastic states.
Pseudoinclusions may be single or multiple. A nonspecific finding encountered in many different types of malignancies as well as some benign conditions. U: Mitosis, abnormal, tripolar (arrow). V: Mitosis, abnormal, aneuploid (arrow). W: Karyorrhexis. Fragmentation of the nucleus. W 19 A B C D E F G H Figs. 7A to H. A: Pale cytoplasm. 7B: Dense cytoplasm. C: Biphasic. Two-tone cytoplasm. D: Keratinization. The keratin stains dense cyanophilic, bright yellow-orange, and refractile. E: Endoplasm-ectoplasm in squamous cells (atypical functional differentiation of squamous cells (arrow).