By Michael H. Ebert;Peter T. Loosen;Barry Nurcombe;James F. Leckman
The main obtainable, built-in resource of scientific psychiatric information--completely up to date! present analysis & remedy: Psychiatry, moment version is the last word reference for fast answering day by day questions about psychiatric ailment in either adults and kids. accomplished in scope, but streamlined in its assurance, this time-saving medical significant other reports crucial psychopharmacologic and psychotherapeutic ways to the entire diversity of psychiatric problems. positive factors the best interviewing innovations and techniques vital evaluate, checking out, and decision-making instruments and standards Ready-to-use info on psychiatry and the legislation, mental trying out, emergency psychiatry, comparing babies, and extra Authoritative assurance of developmental psychology, neuropsychopharmacology, psychiatric genetics, psychoanalysis, and different similar parts invaluable part at the rules of comparing and diagnosing sufferers, in addition to remedy concepts middle sections on grownup issues and pediatric psychiatric difficulties NEW! severe updates to key diagnostic, psychopharmacologic, and psychotherapeutic modalities NEW! part on psychiatric perform in designated settings (20081118)
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Extra resources for CURRENT Diagnosis & Treatment: Psychiatry, Second Edition (LANGE CURRENT Series)
84) 95% CI in parentheses. One of the first twin studies of eating disorders described pairwise concordance of 56% in MZ and 5% in DZ pairs (71% and 10% with probandwise figures). 16% of the female second-degree relatives had had anorexia at some point in their lives, a risk considerably higher than the reported population prevalence. The MZ cotwins were much more similar in "body dissatisfaction," "drive to thinness," weight loss, length of amenorrhea, and minimum body mass index. Estimates indicate that roughly 58â 76% of the variance in the liability to AN, and 54â 83% of the variance in the liability to BN, can be accounted for by genetic factors.
It should be noted that all probands had severe childhood-onset OCD, and were referred to the authors for treatment. It is possible that childhood-onset OCD represents a more severe form of the OCD spectrum. Nevertheless, this carefully conducted family study reveals an increased risk of OCD among the first-degree relatives of OCD probands. When OCD occurs in the familial context of Tourette syndrome, it may be part of the spectrum of Tourette syndrome. However, most OCD occurs in individuals who have no first-degree relatives affected by Tourette's.
Folstein reported that the linkage on 7q was specific to families in which the proband had a specific language disorder (usually reading difficulty along with later-onset autism). It is notable that the linked region includes the gene recently dubbed "speech 1" also known as FOXP2 and known to be a transcription factor), which was recently found to be associated with specific language disorder. A significant site has been found on chromosome 2q32. 3, and near the centromere of chromosome 19. An autistic phenotype found in individuals with the chromosomal duplications of Prader-Willi/Angelman syndrome on 15q11-q13 has focused considerable research in this region of the genome.