Diagnostic Issues in Dementia: Advancing the Research Agenda by Trey Sunderland, Dilip V. Jeste, Olusegun Baiyewu, Paul J.

By Trey Sunderland, Dilip V. Jeste, Olusegun Baiyewu, Paul J. Sirovatka, Darrel A. Regier

A part of the recent sequence Advancing the learn schedule for DSM-V, Diagnostic matters in Dementia includes 9 chapters with examine feedback for attention for the approaching DSM-V procedure, reflecting the nascent attempt towards a brand new diagnostic nomenclature within the nonetheless swiftly evolving box of dementia.

right here, 18 specialists supply severe items of the dementia diagnostic tale: Alzheimer's sickness and the getting older mind, the demanding situations of fixing our normal definition of dementia, diagnostic nomenclature, the turning out to be proof for light cognitive impairment as an identifiable entity appropriate for inclusion in DSM-V, neuropsychological trying out, behavioral syndromes and the necessity to higher concentration applicable remedy, biomarkers in dementia for inclusion in diagnostic standards, particular imaging modalities, and the sobering statement that, regardless of the super explosion of knowledge during this box, genetic profiles with the exception of infrequent Mendelian problems aren't but able to make titanic contributions to nosology.

in the colossal and quickly increasing literature of dementia, this remarkably concise and insightful assortment stories modern day and indicates instructions for tomorrow's vital diagnostic and study matters in dementia, and as such is a "must learn" for clinicians and researchers alike.

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Additional info for Diagnostic Issues in Dementia: Advancing the Research Agenda for DSM-V

Sample text

Dementia: suggested modified definition from the International Classification of Diseases, 10th Revision (ICD-10) Dementia is a syndrome due to disease of the brain, usually of a chronic or progressive nature, in which there is disturbance of multiple higher cortical [functions] capacities, generally including memory, thinking, orientation, comprehension, calculation, learning capacity, language, and judgment. Consciousness is not [clouded] compromised. The impairments of cognitive capacities are accompanied by deficits in executive functioning and, depending on the severity of the condition, may be accompanied by numerous other functional losses in complex and basic skills.

Saved by Clinical Judgment? The CSHA investigators stated that they used DSM-III-R criteria for dementia. As noted above, these are very similar to DSM-IV criteria. Yet, the figure shows that nearly half of the patients with dementia did not meet DSM-IV or any other set of criteria strictly applied. The “clinical consensus” of experts diagnosed dementia in 393 participants. However, strict application of the “DSM-IV criteria” found only 256 case participants, including 56 whom the experts did not characterize as having dementia.

Although the last mentioned are not a defining feature, they can complicate dementia, adding significantly to the burden or difficulty of its care. 2. The deficit represents a state of decline from a previously established level of abilities. Dementia is thus differentiated from syndromes that result from the failure of development of adequate cognitive or intellectual abilities. The decline is usually evident directly but can also be inferred from an educational, social, or occupational history that implies substantially better premorbid functional abilities.

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