Histological Analysis of Endocrine Disruptive Effects in by Daniel R. Dietrich, Heiko O. Krieger(auth.)

By Daniel R. Dietrich, Heiko O. Krieger(auth.)

  • Timely identify assembling the mixed wisdom of a few of the top experts within the box of small fish replica - a major subject for threat review and registration of chemical, agricultural, and pharmaceutical compounds
  • Provides tips at the microscopic constitution of dwelling tissue and evaluate of the reproductive glands of small laboratory fish
  • Includes state of the art technological know-how in addition to adequate anatomical and physiological history for knowing and reading try effects
  • Helps standardize the translation of effects from aquatic bioassays and box observations, so one can additionally make clear inconsistencies within the present clinical literature

Note: CD-ROM/DVD and different supplementary fabrics will not be incorporated as a part of book file.Content:
Chapter 1 creation (pages 1–6):
Chapter 2 Fish Species of curiosity (pages 7–18):
Chapter three Sexual selection, Differentiation, and Gonadal improvement (pages 19–65):
Chapter four girl Gonad Anatomy and Morphology (pages 66–87):
Chapter five Male Gonad Anatomy and Morphology (pages 88–114):
Chapter 6 Endocrine?Disrupting Compounds (pages 115–246):
Chapter 7 decision of results of Exogenous Hormones and Endocrine?Like energetic Compounds (pages 247–253):
Chapter eight review of results in Fish Gonads (pages 254–269):
Chapter nine Experimental layout and statistics (pages 270–294):
Chapter 10 Conclusions (pages 295–299):

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Extra resources for Histological Analysis of Endocrine Disruptive Effects in Small Laboratory Fish

Example text

Indeed, although it is presently unclear whether this can be generalized from medaka and fathead minnows to all teleosts, mitosis and meiosis of germ cells apparently take place earlier in ovaries than in testes [5]. For example, in the fathead minnow, ovarian germ cells and testicular germ cells enter into meiosis around 10 to 25 dph and 90 to 120 dph, respectively [93]. 4 Changes in the number of germ cells in medaka, Oryzias latipes, during normal embryonic development. Open circles, embryos and fry containing no germ cells in the meiotic prophase; filled circles, fry containing germ cells in the meiotic prophase.

S. EPA, Revised draft detailed review paper on fish screening assays for endocrine disruption. Battelle, Columbus, OH, 2002. 14. S. Kane, and R. Reimschuessel, Fathead minnow histology atlas: World Wide Web outreach and utilization. Marine Environmental Research, 2000, 50(1):312. 15. S. EPA, Draft detailed review paper on a fish two-generation toxicity test. Battelle, Columbus, OH, 2002. 16. S. EPA, A short-term test method for assessing the reproductive toxicity of endocrinedisrupting chemicals using the fathead minnow (Pimephales promelas).

Spawning is daily and yearround under optimal artificial conditions, even during the winter season; however, maintenance of an optimal photoperiod and temperature regime is key to successful continuous breeding and “normal” gonadal histopathology [22]. , recrudescence following sexual regression) [23]. The Japanese medaka has a relatively well-characterized process of gonadal differentiation and development. 3 Medaka (Oryzias latipes) d-rR strain. Upper, female; lower, male. ) used as an attractive model system to study sexual differentiation [24–28].

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