By George Wald (auth.), Lawrence I. Gilbert, Earl Frieden (eds.)
"The previous order changeth, yielding position to new. " whilst Tennyson wrote this, he was once surprising with the velocity of modem technology else he could have acknowledged the hot is displaced through the more recent. whilst Gilbert and that i amassed the papers for the 1st version of this evaluation of metamorphosis, we aimed to supply a vast foundation upon which the experimental research of the developmental adjustments referred to as metamorphosis may well continue. We have been either acutely aware then that with the recent concepts of biochemistry and with the progressive leap forward to the character of the gene, numerous new chances have been being opened for the exploration of the molecular foundation of improvement. The assets provided via metamorphic alterations provided exact possibilities to track the trail from gene to phenotype. Our expectancies have been excessive. I visited Larry Gilbert and Earl Frieden of their laboratories and observed with envy how a long way complex they have been then within the use of molecular tools of study. I had begun on a distinct method of boost an in vitro try out for thyroid motion on amphibian tissue. yet situations restricted my very own development to the preliminary delim itation of the technical chances of the in vitro method. merely from the sidelines may well I watch the regular if gradual growth of biology in penetrating the maze of molecular occasions in which animal tissues re spond to hormonal and different developmental factors.
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Extra info for Metamorphosis: A Problem in Developmental Biology
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METAMORPHOSIS: AN OVERVIEW 23 shortly afterward, the ecology all are transformed, and frequently in some degree of accord with the animal's evolutionary history. It is interesting to realize how closely these patterns hold together. An aberration in one of them seems to call forth appropriate aberrations in the others. The mud puppy, Necturus maculosus, for example, remains to some degree a permanent larva, never losing its external gills and never emerging from the water. , 1963). The clawed toad, Xenopus laevis, a member of the peculiar family Aglossa, which possesses neither tongue nor teeth, is a purely aquatic form, which, though it metamorphoses, ordinarily never emerges from the water.