New Concepts of Psychostimulant Induced Neurotoxicity by Hari Shanker Sharma (Eds.)

By Hari Shanker Sharma (Eds.)

Published due to the fact that 1959, International overview of Neurobiology is a well known sequence attractive to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led through an across the world popular editorial board, this crucial serial publishes either eclectic volumes made of well timed stories and thematic volumes that target fresh growth in a selected quarter of neurobiology examine.

With contemporary developments in new wisdom, it has develop into obtrusive that psychostimulants and comparable medicinal drugs of abuse are influencing our critical fearful approach (CNS) remarkably and will modify their functionality for long-time. This quantity is the 1st to target substance abuse prompted mind pathology in widest experience because it covers changes in neuronal, glial and endothelial phone services lower than the effect of acute or continual utilization of substance abuse.

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Extra info for New Concepts of Psychostimulant Induced Neurotoxicity

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Mamounas, L. , Siuciak, J. , and Aitar, C. A. (1995). Brain-derived neurotrophic factor promotes the survival and sprouting of serotoninergic axons in rat brain. J. Neurosci. 15, 7929–7939. , Ji, R. , and Lim, G. (2002). Neuronal apoptosis associated with morphine tolerance: Evidence for an opioid-induced neurotoxic mechanism. J. Neurosci. 22, 7650–7661. Martin-Iverson, M. , Todd, K. , and Altar, C. A. (1994). Brain-derived neurotrophic factor and neurotrophin-3 activate striatal dopamine and serotonin metabolism and related behaviors: Interactions with amphetamine.

In turn, the enhanced extravesicular levels of dopamine lead to oxidative stress through the generation of reactive oxygen species and dopamine quinones, and cause the long-lasting neuronal damage. Thus, we propose that acute behavioral INTERNATIONAL REVIEW OF NEUROBIOLOGY, VOL. 1016/S0074-7742(09)88003-3 43 Copyright 2009, Elsevier Inc. All rights reserved. 00 44 KITA et al. observation of subjects immediately following methamphetamine administration may provide insight into the long-lasting toxicity to dopaminergic neurons.

351, 111–114. , and Weizman, A. (2005). The possible role of neurotrophins in the pathogenesis and therapy of schizophrenia. Eur. Neuropsychopharmacol. 15, 319–329(Review). Siuciak, J. , Aitar, C. , Wiegand, S. , and Lindsay, R. M. (1994). Antinociceptive effect of brainderived neurotrophic factor and neurotrophin-3. Brain Res. 633, 326–330. , Clary, D. , Reichardt, L. , Brandabur, M. , Kordower, J. , and Mufson, E. J. (1994). TrkA-immunoreactive profiles in the central nervous system: Colocalization with neurons containing p75 nerve growth factor receptor, choline acetyltransferase, and serotonin.

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