By Akhlaq A. Farooqui
Phytochemicals are health-protecting compounds of plant foundation. they supply style and colour to the fit to be eaten, culmination, vegetation, herbs and drinks. healthiness holding results of phytochemicals are as a result of antiinflammatory, antioxidant, antiviral, antibacterial, anticarcinogenic, and mobile fix houses. there was substantial curiosity in defining organic actions of phytochemicals on the molecular point. the results of phytochemicals might be conducive, additive, synergistic, and adversarial. via those houses, phytochemicals modulate mobile differentiation, proliferation, oxidative rigidity, irritation and apoptosis. This ebook provides an built-in view on molecular mechanisms of worthy results of phytochemical motion in acute and persistent human illnesses.
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Extra resources for Phytochemicals and Human Health: Pharmacological and Molecular Aspects - A Tribute to Late Professor Bimal Kumar Bachhawat
Yu. Theoretical elucidation of DPPH radical scavenging activity difference of antioxidant xanthones, QSAR Combinatorial Science 2005, 24, 826-830. ; Kawasata, J. DPPH radical scavenging reaction of hydroxy- and methoxy chalcones. Bioscience and Biotechnology of Biochemistry 2006, 70, 193-202. -Y. Selection of theoretical parameter characterizing scavenging activity of antioxidants on free radicals. Journal American Oil Chemists Society 1998, 75, 17051709. G. Liquid – phase theoretical antioxidant activity trend of some cinnamic acid antioxidants.
Identification and evaluation of antioxidant, analgesic/anti-inflammatory activity of the most active ninhydrin-phenol adducts synthesized. Bioorganic and Medicinal Chemistry 2006, 14, 7113-7120. I. Structure-activity relationships of new 4-hydroxy-bis-coumarins as radical scavengers and chain-breaking antioxidants. BIOCHIMIE 2010, 92, 1138-1146. S. Structure- activity relationship of some dihydroxy coumarins. Correlation between experimental and theoretical data and synergistic effect. BIOCHIMIE 2010, 92, 1089-1100.
65% [5,15]. Model 4c - Quantum Chemical Calculations The highest radical-scavenging activity of quercetin derivatives correlates with quantumchemical calculations [17,21,22,29,43-45], indicating that in case of catecholic structure of ring B the rest of molecule doesn‘t affect its ability to scavenge free radicals. The latter can be explained with possible formation of ortho - quinone as a result of homo-disproportionation reaction of semiquinone radicals, formed in the ring B. The important role of the catecholic structure in ring B of a flavonol was demonstrated in case of kaempferol and isorhamnetin, which antiradical capacities are significantly lower (no formation of o-quinone is possible) than those for quercetin and its 3-O-glycosides.